Australia sealed victory in their three-Test series against England as they won the decider 69-56 in Bendigo, Victoria.
Jess Thirlby's England side were full of confidence going into the game after their impressive 61-59 win in Sydney on Sunday.
But world champions Australia put on a clinical display, outscoring the Roses in every quarter to set up a convincing win.
"It is disappointing we couldn't back up such a strong performance in Sydney," England captain Fran Williams told Fox Sports.
"I know a few of us will feel we have let ourselves down today. We maybe let them get on top of us and outmuscle us.
"But I am just super proud of the effort. Winning last week was massive in our history. Doing that in front of an Australian crowd, which is a hard place to come and play.
"I feel like some of our young guns have stood up and that is really exciting."
Australia goal attack Kiera Austin was named player of the match after shooting 24 goals and a further 15 goal assists.
England now head to New Zealand for another three-match series, which starts in Auckland on Sunday.